ANOLES

Yes. "ANOLES" is in the ENABLE word list, accepted by Words With Friends and most open Scrabble apps. It scores 6 points in Scrabble and 8 points in Words With Friends.

In Scrabble, "ANOLES" is worth 6 points before bonuses. In Words With Friends, it's worth 8 points. Played on a triple-word-score, the Scrabble value becomes 18.

Any of the Anolis genus of arboreal American lizards (such as the American chameleon) from the iguana family which feature a brightly colored dewlap and color-changing ability.

1 anagram can be formed using the same letters as ANOLES: LANOSE.